A new aliphatic alcohol and cytotoxic chemical constituents from Acorus gramineus rhizomes.

نویسندگان

  • Ki Hyun Kim
  • Hee Rae Kang
  • Hee Jeong Eom
  • Chung Sub Kim
  • Sang Un Choi
  • Kang Ro Lee
چکیده

A new aliphatic alcohol, (2R,6R)-oct-7-ene-2,6-diol (1), and seven other known compounds (2-8) were isolated from Acorus gramineus rhizomes. The structure of 1 was elucidated by a combination of extensive spectroscopic analyses, including 2D NMR, HR-MS, and the modified Mosher's method. Compounds 3-8 displayed consistent antiproliferative activities against the cell lines tested with IC50 values ranging from 7 to 48 μm.

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عنوان ژورنال:
  • Bioscience, biotechnology, and biochemistry

دوره 79 9  شماره 

صفحات  -

تاریخ انتشار 2015